Category: Current Projects
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A synthetic genomics approach to investigate the XDP/TAF1 locus
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Somatic repeat instability as a modifier of XDP pathogenesis
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Development of novel human cellular models of XDP CCCTCT repeat instability
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Identification of small molecule compounds that confer neuroprotection in patient-derived neurons
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Multimodal and Generative AI for Identifying Drug Candidates in XDP
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The neurochemistry and neuropathology in the basal ganglia and cerebellum of XDP brains
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Biostatistical analysis of X-Linked Dystonia-Parkinsonism
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Molecular dissection of lead targets in XDP-relevant platforms
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Silencing the impact of the hexameric repeat associated with XDP in the Taf1 gene
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Phenotypic analysis of a conditional humanized mouse model of X-linked Dystonia-Parkinsonism